Japan
East Asia · Updated April 2026
Planning a trip to Japan? Japan has the lowest infectious-disease risk of the destinations on this site, and CDC lists Hepatitis B as the main travel vaccine to have up to date. Hepatitis A, Japanese encephalitis, and rabies only come into the conversation for specific plans like street-food travel, rural stays, or farm and forest activities. See a travel doctor 4–6 weeks before you leave so they can decide what, if anything, you need.
There is no malaria in Japan. Dog rabies is not common, and tick-borne encephalitis is present but CDC does not currently recommend the vaccine for travel to Japan.
Required for entry
No vaccines are currently required for entry to Japan from most countries.
Recommended for most travellers
CDC advises these for all visitors to Japan.
Recommended for some travellers
Depends on your itinerary, activities, duration, or health.
Hepatitis A
A contagious liver infection spread through contaminated food and water. Most travellers to regions with less reliable sanitation should get this vaccine.
Japanese Encephalitis
A mosquito-borne virus affecting the brain, found in rural parts of Asia. Risk is highest during rice-paddy season in rural areas.
Rabies
A fatal viral disease spread through the bite or scratch of an infected animal — most often dogs, bats, or monkeys. Pre-travel vaccination simplifies treatment after exposure.
Routine vaccines to be up to date on
CDC advises every international traveller to have these current.
Measles-Mumps-Rubella (MMR)
Diphtheria-Tetanus-Pertussis
Polio
Flu (Influenza)
Chickenpox (Varicella)
Shingles
COVID-19
Entry requirements
For US citizens. Non-US travellers should check their government's guidance.
Japan has the lowest infectious-disease risk of our featured destinations. CDC lists Hepatitis A only for street-food enthusiasts or rural travellers, not for most city itineraries. Dog rabies is not common in Japan. Tick-borne encephalitis is present — avoid tick exposure if you'll be hiking, but CDC does not recommend the vaccine for travel to Japan.
Source: CDC Travelers' Health — Japan.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.