Cholera
A bacterial infection spread through contaminated water, causing severe diarrhoea. Rare in travellers but worth considering for aid workers or travel to areas with active outbreaks.
What it is
Cholera is a bacterial infection that can cause sudden, severe watery diarrhoea. Without treatment it can lead to dangerous dehydration quickly.
How it spreads
Through water or food contaminated with the stool of an infected person. Outbreaks happen most often in places with damaged water systems — after disasters, in refugee camps, or in areas with poor sanitation.
Dosing & timing
- Primary series
- A single oral dose, taken at least 10 days before travel.
- Boosters
- Long-term protection beyond a few months is uncertain. If you remain at risk, talk to your doctor about another dose.
- Before you travel
- At least 10 days before potential exposure.
Who should consider it
CDC recommends the vaccine for travellers aged 2 to 64 going to an area with active cholera transmission. It is not routinely advised for most travellers — careful food, water, and hand hygiene is the main protection.
Countries where CDC recommends this
Click any country for its full vaccine list.
Recommended for some travellers
Side effects and safety
Common (most resolve in a day or two)
- Tiredness
- Headache
- Mild stomach upset or nausea
Serious but rare
- Severe allergic reaction (very rare)
Who should not get it
Skip it if you have had a severe allergic reaction to a previous dose or any ingredient.
Common questions
Should every traveller to a developing country get a cholera vaccine?
No. Cholera is rare in regular travellers. The vaccine is mainly for aid workers or people heading into active outbreak zones.
How do I avoid cholera without the vaccine?
Drink only sealed bottled or boiled water, eat freshly cooked hot food, peel your own fruit, and wash your hands often.
Is treatment available if I catch it?
Yes. Rapid rehydration with oral rehydration salts saves most people. Antibiotics help in severe cases.
Plan ahead: Talk to a travel health doctor 4 to 6 weeks before departure if you are heading to a known outbreak area or doing aid work.
Source: CDC — Cholera.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.