Equatorial Guinea
Central Africa · Updated April 2026
For most travellers to Equatorial Guinea, CDC recommends hepatitis A, hepatitis B, typhoid and yellow fever vaccines. Rabies may be advised depending on your activities, and antimalarial medicine is recommended for all travellers. Yellow fever may also be required for entry if arriving from a risk country. See a travel health professional 4–6 weeks before departure.
Malaria risk is present year-round in all areas, so take antimalarial medicine and prevent mosquito bites throughout your trip.
Required for entry
No vaccines are currently required for entry to Equatorial Guinea from most countries.
Exception: Proof of Yellow Fever vaccination — Required for travellers arriving from a country with risk of yellow fever virus transmission. Not required for direct travel from the United States; CDC recommends the vaccine for most travellers.
Recommended for most travellers
CDC advises these for all visitors to Equatorial Guinea.
Hepatitis A
A contagious liver infection spread through contaminated food and water. Most travellers to regions with less reliable sanitation should get this vaccine.
Two doses at 0 and 6–12 months. Over 90% of people develop protective antibodies within a month of the first dose, so one dose is usually enough for the trip itself. No booster needed after the full series.
Blood & Body FluidsHepatitis B
A liver infection spread through blood, sexual contact, and contaminated medical or cosmetic equipment. Recommended for most travellers, especially those with longer stays or possible medical exposure.
The full series is three doses over 6 months. An accelerated 4-dose schedule (0, 7, 21 days, 12 months) is available when combined with Hepatitis A. Partial protection starts after the first dose.
Food & WaterTyphoid
A bacterial infection spread through food and water contaminated with the faeces of an infected person. Risk is higher in rural areas and when eating with locals.
The injected vaccine is a single dose at least 2 weeks before travel and lasts 2 years. The oral version is four capsules taken every other day, completed at least a week before travel, and lasts 5 years. Neither is 100% effective — safe food and water habits still matter.
Recommended for some travellers
Depends on your itinerary, activities, duration, or health.
Malaria
Not a vaccineMalaria is present in all areas. CDC recommends prescription antimalarial medicine for all travellers. Chloroquine-resistant P. falciparum is the main species. Options include atovaquone-proguanil, doxycycline, mefloquine or tafenoquine.
Food & water safety
High riskTap water and ice are generally unsafe. Stick to sealed bottled water, boiled water, or water from a reliable filtration system. Avoid raw salads, unpeeled fruit, raw shellfish, and street food from vendors with poor hygiene. Wash hands thoroughly before eating.
Routine vaccines to be up to date on
CDC advises every international traveller to have these current.
Measles-Mumps-Rubella (MMR)
Diphtheria-Tetanus-Pertussis
Polio
Flu (Influenza)
Chickenpox (Varicella)
Shingles
COVID-19
Entry requirements
For US citizens. Non-US travellers should check their government's guidance.
CDC flags leptospirosis and schistosomiasis from fresh water, African sleeping sickness, African tick-bite fever, dengue, hantavirus, tuberculosis and rabies from dogs. Avoid contaminated fresh water, bug bites and rodents.
Source: CDC Travelers' Health — Equatorial Guinea.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.