Iran

Western Asia · Updated April 2026

See a travel doctor 4–6 weeks before you leave.

Current alert — Global Measles

Measles cases are rising in many countries around the world. Ensure MMR vaccination is complete at least two weeks before departure.

For most travellers to Iran, CDC recommends hepatitis A vaccination alongside routine vaccines. Depending on your itinerary, hepatitis B, typhoid and rabies may also be advised. Malaria precautions apply in some rural areas. See a travel health professional 4–6 weeks before departure to plan your vaccinations.

Malaria risk is present March–November in certain rural areas, with chemoprophylaxis advised for Sistan-Baluchestan Province.

Required for entry

No vaccines are currently required for entry to Iran from most countries.

Exception: Proof of Yellow Fever vaccination Required for travellers aged 9 months or older arriving from a country with risk of yellow fever virus transmission.

Recommended for most travellers

CDC advises these for all visitors to Iran.

Recommended for some travellers

Depends on your itinerary, activities, duration, or health.

Malaria

Not a vaccine

Malaria transmission occurs March–November in certain rural areas. CDC advises chemoprophylaxis (atovaquone-proguanil, doxycycline, mefloquine or tafenoquine) for Sistan-Baluchestan Province near the Pakistan border; other historically affected areas need only mosquito-bite precautions.

Discuss prescription chemoprophylaxis with a travel doctor if your itinerary includes risk areas.

Food & water safety

Moderate risk

Exercise food and water precautions, particularly in rural areas and budget accommodation. Bottled or treated water is advisable. Avoid raw shellfish and salads washed in tap water. Choose cooked food served hot.

Routine vaccines to be up to date on

CDC advises every international traveller to have these current.

Measles-Mumps-Rubella (MMR)
Two doses at least 28 days apart, ideally completed at least 2 weeks before travel. Adults born before 1957 or with documented immunity are already considered protected.
Diphtheria-Tetanus-Pertussis
A single Tdap or Td booster, effective within days. Adults should have a booster every 10 years — or after 5 years if you've had a dirty wound or burn. Pregnant travellers should receive Tdap during every pregnancy.
Polio
A single lifetime adult IPV booster for travellers to at-risk countries. For some destinations, the booster must be received 4 weeks to 12 months before departure and documented on an International Certificate of Vaccination.
Flu (Influenza)
An annual dose at least 2 weeks before travel to areas with active flu circulation. A single current-season vaccine covers travel to either hemisphere.
Chickenpox (Varicella)
Two doses at least 28 days apart for adolescents and adults without immunity. Children get doses at 12–15 months and 4–6 years. Two documented doses protect most people for life.
Shingles
Two doses of Shingrix 2–6 months apart. Protection stays high for at least 7 years. Adults 19+ with weakened immune systems can use a faster schedule (2nd dose 1–2 months after).
COVID-19
Follow the current CDC schedule for your age and risk group. If you had COVID-19 recently, you may delay vaccination for up to 3 months from the onset of infection.

Entry requirements

For US citizens. Non-US travellers should check their government's guidance.

Only if arriving from a YF-risk country

Practise strict food and water safety and prevent insect bites. Risks include schistosomiasis from freshwater, leishmaniasis from sand flies, dengue, Crimean-Congo haemorrhagic fever, rabies, tuberculosis and MERS.

Also in Western Asia

Source: CDC Travelers' Health — Iran.

Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.