Nepal
South Asia · Updated April 2026
Planning a trip to Nepal? CDC recommends Hepatitis A and typhoid vaccines for most travellers because food- and water-borne illness is the main concern outside large hotels. Your doctor may also discuss Hepatitis B, Japanese encephalitis, cholera, or rabies depending on your itinerary and activities. See a travel doctor 4–6 weeks before departure so they can match the plan to your trip.
Malaria risk is limited to lowland Sudurpashchim and Karnali provinces. Kathmandu, Pokhara, and Himalayan trekking routes are not malaria zones.
Required for entry
No vaccines are currently required for entry to Nepal from most countries.
Recommended for most travellers
CDC advises these for all visitors to Nepal.
Hepatitis A
A contagious liver infection spread through contaminated food and water. Most travellers to regions with less reliable sanitation should get this vaccine.
Two doses at 0 and 6–12 months. Over 90% of people develop protective antibodies within a month of the first dose, so one dose is usually enough for the trip itself. No booster needed after the full series.
Food & WaterTyphoid
A bacterial infection spread through food and water contaminated with the faeces of an infected person. Risk is higher in rural areas and when eating with locals.
The injected vaccine is a single dose at least 2 weeks before travel and lasts 2 years. The oral version is four capsules taken every other day, completed at least a week before travel, and lasts 5 years. Neither is 100% effective — safe food and water habits still matter.
Recommended for some travellers
Depends on your itinerary, activities, duration, or health.
Hepatitis B
A liver infection spread through blood, sexual contact, and contaminated medical or cosmetic equipment. Recommended for most travellers, especially those with longer stays or possible medical exposure.
Japanese Encephalitis
A mosquito-borne virus affecting the brain, found in rural parts of Asia. Risk is highest during rice-paddy season in rural areas.
Cholera
A bacterial infection spread through contaminated water, causing severe diarrhoea. Rare in travellers but worth considering for aid workers or travel to areas with active outbreaks.
Rabies
A fatal viral disease spread through the bite or scratch of an infected animal — most often dogs, bats, or monkeys. Pre-travel vaccination simplifies treatment after exposure.
Malaria
Not a vaccineActive transmission in Sudurpashchim and Karnali provinces below 2,000 m. No risk in Kathmandu, Pokhara, or on typical Himalayan treks.
Routine vaccines to be up to date on
CDC advises every international traveller to have these current.
Measles-Mumps-Rubella (MMR)
Diphtheria-Tetanus-Pertussis
Polio
Flu (Influenza)
Chickenpox (Varicella)
Shingles
COVID-19
Entry requirements
For US citizens. Non-US travellers should check their government's guidance.
Dog rabies is common in Nepal. Dengue, leptospirosis, leishmaniasis, and tuberculosis are present. Standard food, water, and bug-bite precautions matter.
Source: CDC Travelers' Health — Nepal.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.