Mpox
A viral illness spread through close skin-to-skin contact, often during sex. CDC advises vaccination for travellers anticipating new sexual partners or exposure at large public events in at-risk regions.
What it is
Mpox is a viral illness that causes a painful rash, fever, and swollen glands. Most people recover in 2 to 4 weeks, but it can be more serious in some.
How it spreads
Mostly through close skin-to-skin contact, often during sex. It can also spread through respiratory droplets in close contact and from contaminated bedding or clothing.
Dosing & timing
- Primary series
- Two shots, 4 weeks apart.
- Boosters
- No booster needed — protection appears to last at least 7 years.
- Before you travel
- Best protection comes about 2 weeks after the second dose, so start the series at least 6 weeks before travel.
Who should consider it
CDC recommends the vaccine for people with known or suspected exposure, recent sexual partners of someone diagnosed, gay or bisexual men and transgender or nonbinary people with multiple recent partners or a recent STI, and travellers heading to countries with a clade I outbreak who anticipate sex with new partners or attending events where that is likely.
Countries where CDC recommends this
Click any country for its full vaccine list.
Recommended for some travellers
Side effects and safety
Common (most resolve in a day or two)
- Soreness, redness, or itching where the shot was given
- Headache
- Tiredness
- Muscle aches
Serious but rare
- Severe allergic reaction (very rare)
Who should not get it
Skip it if you have had a severe allergic reaction to a previous dose or any ingredient.
Common questions
Do I need mpox vaccination for a regular holiday?
Most travellers do not. CDC recommends it mainly when sexual exposure or close-contact events are part of your plans in an outbreak area.
How long does protection last?
Evidence suggests protection lasts at least 7 years and a booster is not needed.
Can I still catch mpox after vaccination?
It is still possible, but cases are usually milder. Avoid close contact with anyone who has a new rash or skin lesions.
Plan ahead: Talk to a travel health doctor 4 to 6 weeks before departure — ideally 6 weeks or more so you can complete both doses.
Source: CDC — Mpox.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.