Sierra Leone
West Africa · Updated April 2026
Yellow fever vaccination is required for entry to Sierra Leone, and CDC also recommends hepatitis A, hepatitis B and typhoid for most travellers. Antimalarial medicine is advised, and some travellers may need rabies or mpox vaccines depending on their plans. See a travel health doctor 4-6 weeks before departure.
Malaria risk is present year-round throughout the country, so take preventive medicine and avoid mosquito bites.
Required for entry
Recommended for most travellers
CDC advises these for all visitors to Sierra Leone.
Hepatitis A
A contagious liver infection spread through contaminated food and water. Most travellers to regions with less reliable sanitation should get this vaccine.
Two doses at 0 and 6–12 months. Over 90% of people develop protective antibodies within a month of the first dose, so one dose is usually enough for the trip itself. No booster needed after the full series.
Blood & Body FluidsHepatitis B
A liver infection spread through blood, sexual contact, and contaminated medical or cosmetic equipment. Recommended for most travellers, especially those with longer stays or possible medical exposure.
The full series is three doses over 6 months. An accelerated 4-dose schedule (0, 7, 21 days, 12 months) is available when combined with Hepatitis A. Partial protection starts after the first dose.
Food & WaterTyphoid
A bacterial infection spread through food and water contaminated with the faeces of an infected person. Risk is higher in rural areas and when eating with locals.
The injected vaccine is a single dose at least 2 weeks before travel and lasts 2 years. The oral version is four capsules taken every other day, completed at least a week before travel, and lasts 5 years. Neither is 100% effective — safe food and water habits still matter.
Recommended for some travellers
Depends on your itinerary, activities, duration, or health.
Rabies
A fatal viral disease spread through the bite or scratch of an infected animal — most often dogs, bats, or monkeys. Pre-travel vaccination simplifies treatment after exposure.
Mpox
A viral illness spread through close skin-to-skin contact, often during sex. CDC advises vaccination for travellers anticipating new sexual partners or exposure at large public events in at-risk regions.
Malaria
Not a vaccineMalaria transmission occurs in all areas of Sierra Leone, predominantly chloroquine-resistant P. falciparum. CDC recommends antimalarial medicine such as atovaquone-proguanil, doxycycline, mefloquine or tafenoquine.
Food & water safety
High riskTap water and ice are generally unsafe. Stick to sealed bottled water, boiled water, or water from a reliable filtration system. Avoid raw salads, unpeeled fruit, raw shellfish, and street food from vendors with poor hygiene. Wash hands thoroughly before eating.
Routine vaccines to be up to date on
CDC advises every international traveller to have these current.
Measles-Mumps-Rubella (MMR)
Diphtheria-Tetanus-Pertussis
Polio
Flu (Influenza)
Chickenpox (Varicella)
Shingles
COVID-19
Entry requirements
For US citizens. Non-US travellers should check their government's guidance.
Take malaria precautions and avoid mosquito and tick bites (dengue, African tick-bite fever). Avoid contaminated freshwater (schistosomiasis, leptospirosis), animals and sick people, as Ebola, Marburg, Lassa fever and rabies are present.
Source: CDC Travelers' Health — Sierra Leone.
Disclaimer:This information is for general guidance only, based on CDC Travelers' Health. It does not replace advice from a qualified travel health professional. Consult a doctor 4–6 weeks before your trip.